English
Spanish
French
German
Arabic
Hindi
Korean
Russian
Dutch
Investigate the development status of the domestic pharmaceutical packaging industry, and propose improvement plans for the problems of poor stability and low measurement accuracy of the automatic filling production line of small and medium-sized pharmaceutical manufacturers, which will help improve the production efficiency of the enterprise, and address the key components of the transmission mechanism —Axis for design calculations.
As a special commodity that is indispensable in daily life, the quality and safety of medicines are directly related to people’s health, and medicines are easily affected by external factors such as temperature, humidity and microorganisms during the production and distribution process, resulting in reduced efficacy or even contamination. . Therefore, the state has issued a series of policies and regulations for the production and packaging of pharmaceuticals, and strictly regulated the relevant requirements. With the rapid development of my country’s pharmaceutical industry, the types and output of drugs continue to increase, and the requirements of drug manufacturers for automatic drug production equipment are gradually increasing. Therefore, the development of an automatic drug filling device is of great significance to improve the production efficiency of drug manufacturers and meet market demand.
Part 1 Research Significance Of Pharmaceutical Automatic Filling Production Line
1.1 Current Status Of Domestic Pharmaceutical Packaging Industry
With the vigorous development of China’s pharmaceutical industry, the pharmaceutical packaging industry is also developing rapidly, far exceeding the average development level of all countries in the world. According to market survey data, there are three main types of packaging currently used in the Chinese pharmaceutical market: glass bottle packaging, plastic bags and plastic bottle packaging for infusions, aluminum-plastic blister packaging, and plastic bottle packaging for western medicine tablets.
Glass material is a material with stable performance, easy disinfection, and good barrier properties. It can play a better protective role in pharmaceutical packaging and can effectively guarantee the chemical properties of pharmaceuticals. Therefore, it is widely used as pharmaceutical packaging materials, such as Common oral liquid bottles, infusion injection bottles, etc.
Metal materials are widely used in pharmaceutical packaging. The most common one is aluminum, which has the characteristics of metallic luster, beautiful appearance, light weight, easy to open, light-shielding, and good moisture-proof performance. Usually, aluminum-plastic blisters and aluminum-plastic composite bags are used. etc. to use.
Plastic materials have the characteristics of strong plasticity, easy processing, small quality, and low price, especially the advantages of strong plasticity, so that they can be processed into products of different specifications and shapes, which can better meet the needs of enterprises. One of the most widely used materials. Taking the “medicine capital” Zhangshu City as an example, statistics show that as of June 2020, Zhangshu City has more than 260 pharmaceutical manufacturers of various types; in 2019, the total expenditure on pharmaceutical packaging related business was 3.07 billion yuan, a year-on-year increase of 18.1%. Among them, most pharmaceutical manufacturers use plastic bottle filling.
1.2 Development Status Of Automatic Drug Packaging Machinery
Pharmaceutical packaging machinery is a machinery that performs all or part of the packaging process for pharmaceuticals. Drug packaging automation is an important link in the realization of drug automation production. The development of drug packaging machinery automation has a significant effect on improving labor production efficiency and reducing labor intensity. It will help improve the production efficiency of drug manufacturers and further strengthen their market. Competitiveness. At the same time, the automation of drug packaging can effectively reduce the influence of external factors on drugs in the production process, so that the safety of drug production can be further guaranteed.
However, the survey shows that at present, the packaging machinery of most small and medium-sized pharmaceutical manufacturers generally has problems such as low degree of automation and inaccurate measurement. Through interviews and surveys of some pharmaceutical production enterprises in Zhangshu City, the data show that most enterprises still use manual packaging, which is inefficient and poses a large health and safety hazard. The filling production line equipment that costs money is generally idle. It is used to cope with the inspection of the relevant departments at the higher level, making this type of equipment useless. It is understood that the main reason for this phenomenon is that the purchased canning production line equipment has problems such as poor operability, unstable performance, and low measurement accuracy.
1.3 Research Significance Of Automatic Filling Production Line
In view of the current actual needs of the pharmaceutical production enterprises in Zhangshu City for the automatic packaging production line, such as easy operation, strong work reliability, and high filling accuracy, the existing production line transmission device is improved, mainly including the transmission mechanism, metering device and control system. Design and develop a new type of mechanical automatic transmission mechanism to speed up the automatic filling of medicines, improve the accuracy of automatic metering, simplify the operation process, and ensure efficient filling of granules, pastes, liquids or solid-liquid mixtures, etc. And accurate measurement, realize the full automation of the production process of the pharmaceutical filling machine, change the current manual filling mode or semi-automatic mode, and improve the production level of the enterprise.
Part 2 Improvement And Development Of Pharmaceutical Automatic Filling Production Line
2.1 Basic Process Of Drug Automatic Filling Production
In the production process of medicine filling, the mixing mechanism will stir the material evenly, and the material of corresponding quality will be put into the material bottle through the filling mechanism, and sent to the drug filling station. bit stop. If the test result shows that the quality of the material is lower than the set value, the medicine will continue to be added until it reaches the standard, and the bottle will continue to be conveyed forward, and then sealed by the sealing mechanism to complete the entire filling process.
The drug automatic filling production line mainly includes a conveying mechanism, an automatic filling mechanism, a cap unscrambling device and a sealing device. Among them, the conveying mechanism is mainly composed of three parts: a filling metering device, a bottle conveying mechanism and a frame. The filling metering device is responsible for the metering of materials and the control of the filling quantity of medicines, and timely adding materials to the bottles with insufficient filling materials; the bottle conveying mechanism is mainly responsible for the supply and distribution of the bottles; the frame is the supporting part.
2.2 The Main Problems Existing In The Existing Automatic Filling Equipment
At present, the filling equipment used by pharmaceutical manufacturers is mainly divided into linear type and rotary type.
In the linear filling equipment, the packaging container mainly performs intermittent linear motion, that is, a group of medicine bottles with a rated quantity moves forward in a straight line following the conveyor belt. At the same time, the photoelectric sensor is used to monitor the position of the material bottle. When it is in the corresponding position, the multi-head filler will fill the medicine. After filling, the group of medicine bottles continues to move forward to enter the next link. Although the linear automatic filling machine has a simple structure, the space utilization rate is low, and when the filling action is performed, the medicine bottle needs to wait for the filling to be completed, the production efficiency is greatly reduced, and it cannot meet the needs of large-scale production operations.
Rotary filling equipment has the characteristics of small footprint and continuous filling, that is, the material bottle can complete the filling operation while following the conveying device along the circumferential direction at a constant speed, and is suitable for continuous production of various liquid materials . The equipment has high space utilization rate, high production efficiency and high production efficiency, and can meet the needs of large-scale filling operations. However, the structure of the continuous rotary filling machine is relatively complicated, which requires high design and manufacturing costs, and is only suitable for the filling of a single type of material, that is, the filling of liquid medicinal materials.
2.3 Improvement Plan For Automatic Filling Equipment
In view of the characteristics and outstanding problems of various types of filling equipment currently available in pharmaceutical production enterprises, in order to meet the needs of domestic small and medium-sized enterprises for filling equipment automation, high efficiency, low cost, and strong applicability, an economical and practical filling equipment was improved and designed. automatic filling equipment. First of all, in order to achieve higher filling efficiency and reduce the footprint of the equipment in the factory building, the filling machine can be designed as a rotary type. Secondly, in order to reduce costs and expand the scope of application of materials, the movement mode of the filling machine is selected as intermittent. After comprehensive consideration, it is finally determined to change the automatic filling equipment into an intermittent rotary filling machine.
Part 3 Conclusion
With the development of pharmaceutical production enterprises, the output of pharmaceuticals puts forward higher requirements for the pharmaceutical packaging production line. In view of the problems of low automation, low efficiency and low accuracy of the current pharmaceutical filling production line, the production line is improved to realize the operation of the pharmaceutical packaging production line. Convenience, reliability, and high accuracy are helpful to provide technical assistance to related enterprises and serve the local economy.