High Shear Mixer Granulator: The Complete User Guide

What is High Shear Mixer Granulator ?

The high shear mixer granulator is to use the vacuum conveyor to transfer the material into the container through the vortex effect generated by the rotation of the stirrer to make it fully mixed. After adding the binder, in the intersection area, the granulating cutter will affect the churning material. The dough is fully broken and cut into uniform and dense spherical particles.

It integrates mixing and granulation. It is suitable for mixing and granulating powdered materials in pharmaceutical, chemical, light industry and other industries, and it is also suitable for dry powder mixing. This machine can meet the requirements of the mixing and granulation of tablets and capsules in the pharmaceutical industry.

The GM series high platform high speed mixer is mainly composed of machine frame, material cylinder and cylinder cover function components, mixing paddle and its driving device, granulating knife and its driving device, discharging device, electric control system, etc.

The GM series high position wet type mixing granulator is applied for mixing and granulating powder materials in such industries as medicine, food and chemical industry, and is also used for mixing dry powders, it is used for other industries for mixing and granulating.

The Features Of High Shear Mixer Granulator

1. The produced particles are strong, rounded, uniform in particle size, and the product yield is extremely high.
2. The mixing and granulation are completed in one step and the material is automatically discharged.
3. Equipped with advanced Z-shaped blades.
4. Fully enclosed production and cleaning are convenient and meet the requirements of “GMP” (2011 version) for pharmaceutical machinery.
Working in a closed state, pneumatic quick opening of the door cover is convenient and quick. The sight glass hole on the door cover is convenient for observing the movement of the material in the container.
5. The agitator makes the material produce strong vortex movement, and the mixing ability is strong and uniform. The side cutter has strong shearing force and quick granulation.
6. The axial sealing effect is good, preventing the medicine from being contaminated by lubricating grease.
7. Touch screen + PLC control system, manual and automatic program operation functions, and can be intelligently upgraded.
8. Have reliable safety interlock protection function.
9. Can be equipped with jacketed pot for heating or cooling.

The Applications Of High Shear Mixer Granulator

This wet mixing granulator is one of the equipments of the solid preparation production process commonly used in the pharmaceutical industry. It has multiple functions such as mixing and granulating. It is mainly used for products of relatively viscous powdery materials and dry powdery materials. Used in pharmaceutical, food, chemical and other industries.

Working Environment Conditions Of High Shear Mixer Granulator

1. Working environment: in the “D” cleanliness environment at the host.
2. Power supply: 3N 50HZ/TN-S 220V/380V three-phase five-wire system allowable voltage fluctuation range 380V+5% -10%.
3. Operating air source: compressed air should be free of oil, water, and impurities, and the pressure should not be less than 0.6MPa.
4. Process air source: In addition to the compressed air which should be free of oil, water and impurities, the system should have a filter device.
5. Clean the water source: drinking water, purified water.

Working Principles Of High Shear Mixer Granulator

The wet mixing granulation process is completed in the same container by the two processes of mixing and granulating. The powdery material is put into the material container from the top of the conical hopper. After the cover is closed, the powder material rotates in the container due to the stirring effect of the stirring paddle. At the same time, the material rolls from the outside to the center in the direction of the cone wall, forming a semi-flow The material is sheared and diffused to achieve sufficient mixing.

During granulation, the powder is gradually moistened due to the injection of the binder, and the properties of the material are changed, which strengthens the extrusion, friction, and kneading of the material by the blade and the barrel wall, and gradually forms a liquid bridge, and the material gradually turns into a loose soft These soft materials with agglomerated structure are not granulated by forced extrusion, but are cut by a pelletizing knife. The soft materials are cut into small and uniform particles in a semi-fluid state to realize the phase transition of the material. Finally, the discharge door is opened, and the wet particles are pushed out of the hopper under the centrifugal action of the paddle.

Main Composition And Material Of High Shear Mixer Granulator

The part of the mixing granulator directly in contact with the material is made of high-quality austenitic stainless steel (SUS304). Other non-metallic materials do not undergo chemical changes with the material, do not corrode, and have sufficient mechanical strength. The outer surface is made of austenite stainless steel wire drawing board. The window adopts non-static transparent material.

The main structure and performance characteristics of the equipment

1. Rack System

It is composed of a frame, an operating stepladder, an overhaul door, etc., and plays a role in equipment protection and operation safety protection in the equipment system.

The motor, reducer, air purification device, and piping system of the transmission system are installed in the chassis. One side of the chassis is equipped with an electrical control box and a pneumatic control box; one side is a movable door for safety protection, installation and maintenance. The bottom of the chassis is equipped with feet, which are equipped with support plates, adjusting bolts, fastening nuts and anchor bolts. The adjusting bolts can quickly adjust the equipment level.

2. Pot Lid System

It is composed of a vacuum feeding interface, a liquid adding gun, an observation mirror, a liquid adding hopper, an air outlet filter system, a locking device, a sealing tape, etc.

Under the pulling of the lid opening cylinder, the lid moves perpendicular to the upper flange surface of the stirring pot. When the lower face of the lid flange is parallel to the upper face of the stirring pot flange, the locking buckle is attached and embedded in the lid The dovetail silicone sealing strip on the lower face of the flange seals the lid and the stirring pot.

3. Mixing System

It consists of a stirring paddle conveying device and a variable speed power device.

The stirring paddle transmission device and power device are placed in the frame under the stirring pot, and the stirring paddle transmission device is directly connected with the variable speed power device; the stirring paddle transmission device is mainly composed of a coupling, a rotating shaft, a bearing seat, an air seal ring, and a compression nut, stirring paddle, etc.

The stirring paddle is a Z-shaped three-blade stirring paddle. As the stirring paddle moves in the pot, the material will roll up and down and rotate in the stirring pot to make three-dimensional movement. Ensure the effective mixing and continuous granulation of powder and other added substances.

The stirring shaft is oil-free sealed. An air-sealing system prevents the leakage of materials in the sealed area, thus ensuring that the operation is carried out without pollution.

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