Key Points Of This Chapter   Fluid bed coating is more challenging than fluid bed granulation and drying.   Traditional overhead sprays are easiest to scale. However, this technology is not suitable for functionally coated dosage forms. The amplification of the spray rate is usually calculated based on the increase in the amount of fluidizing […]

Key Points Of This Chapter   Statistical design of experiments is helpful for process scale-up, but for fluidized beds it is not possible to simply rely on process variables for scale-up, but rather to identify and account for all key sources of variability, to manage the variability through the process, and to predict Product quality

Key Points Of This Chapter   For process control, we must first have a deep understanding of the purpose of the product process, including the attributes of raw materials and auxiliary materials, processing unit attributes, and product quality attributes, so as to formulate clear and effective strategies, and finally choose the appropriate method for implementation.